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What and why use Mycoglannan

April 22, 2017

What is Mycoglannan and how does it work?
It is made up of material, which forms 2 rings surrounding the yeast cell wall. The Mycoglannan is made up of Mannans and B Glucans. 
The outer layer is Mannan Protein also known as mannanoligosaccharide (MOS). 
Mannan is a non-digestible protein carbohydrate, when added to an animals total feed, its complex nature prohibits it being digested by the animal, but makes it available to be used by the good bacteria/flora of the gut. This allows the good bacteria to grow rapidly in the gut and provide an improved defence against harmful bacteria. The animal is now better able to fight against bad bugs. This is referred to as a prebiotic.
A Prebiotic can be described as a biological agent, which stimulates preventative measures within the gut of an animal.
Pathogens enter the animals gut and look for a place on the cells which line the gastrointestinal tract to bind and subsequently colonize and reproduce.
To prevent the establishment of the bad bacteria, it is necessary to stop the binding process. The Mannans do this by getting between the lectins on the bad bacteria and the sugar compounds on the intestinal lining. The lectins attach to the Mycoglannan instead of the sugars on the cell of the gut wall lining. After capturing the pathogens, the Mycoglannan is expelled naturally by the animal through the gut along with other waste materials. 

Due to the production techniques, Mycoglannan material is one of the most consistent and effective MOS on the market.

Mycoglannan acts as a Macrophage –
A macrophage is a cell in the blood stream which destroys and digests pathogens.
The inner layer of the cell wall is made up by the extremely complex carbohydrate 1,3 1,6 Beta-glucan. It has been shown Beta-glucans interact with the immune system to increase its reaction capabilities. 
So the Mycoglannan works to activate the animals’ immune system through the activity of beta-glucans and mannans which are two of the main components of the yeast cell wall. These elements bind to pathogens in the digestive tract and stimulate the immune system to produce antibodies. 

Mycoglannan material is a component of many specialty animal feeds over seas. 
Many of the Sheep farmers in the UK and Ireland are using this cell wall material and finding the benefits overwhelming. They claim that the Mycoglannan material increases the amount of maternal antibodies in the colostrum the ewes are producing, giving the lambs the best form of disease defence possible.
It would be interesting to know whether this follows through to other species.

I have been asked about using other forms of toxin binders such as bentonite and zeolite. Below is a study that was done in a Brazilian university -

Carlos Alberto da Rocha Rosa DVM, Ph.D., Universidad Federal Rural de Rio de Janeiro, Brazil -Adsorbing agents - One of the strategies for reducing the exposure to mycotoxins is to decrease their bioavailability by including various mycotoxin adsorbing agents in the compound feed, which leads to a reduction of mycotoxin uptake as well as distribution to the blood and target organs. Adsorbing agents are also called binding agents, adsorbents, binders, etc. The reduction of mycotoxin bioavailability using various inorganic adsorbents – like bentonite and zeolites - has been thoroughly studied. However, some of these adsorbents can reduce nutritional value of feeds by binding trace minerals, amino acids and vitamins and reducing their bioavailability and even produce dioxins, produce undesirable side effects and they are not considered safe by the European Union. Due to the limitations of mineral adsorption, many studies have been conducted over the last decade on biological adsorbents, in an attempt to obtain greater efficacy and specificity while, at the same time, reduce the impact on nutritional quality compared to mineral adsorbents.

These are not binders we like to use full time, and you can now see why. Within this study it was also discovered that the Mycoglannan material was affective in inhibiting the oestrogenic effect of ZEA(zearalenone) pathogen.

As more research results are published overseas, and the list of pathogens controlled by Mycoglannan material increases, it is being mooted that the product will eventually replace the antibiotics used as growth stimulants. Until these claims are accepted and approved by the APVMA, it would be prudent at this time to expect only the following performance claims and benefits:
- helps maintain a healthy immune system
- supports natural defense
- promotes a healthy gut flora
- maintains and promotes gut health.

Introducing Mycoglannan to an animals feed would be reasonable to assume prevention is better then cure.

I hope you have found this informative and helped you to understand the affects you are seeing with your animals. I hope you can all continue to share the results you are getting with us and others to help us all learn more about the affects of this amazing product.

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